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In silico investigation of potential inhibitor molecules against caseinolytic peptidase B (ClpB) protein
(2024-09-27)Proteins are the most versatile and intricately structured macromolecules among all biologically active systems. Molecular chaperones are distinct proteins that have evolved within cells to facilitate protein folding and ... -
Isolation of ClpB & DnaK bi-chaperones from obligate pathogen Anaplasma phagocytophilum as future therapeutic targets
(2025-04-27)Anaplasma phagocytophilum is an obligate intracellular pathogen that causes Human Granulocytic Anaplasmosis (HGA). Genetic manipulation of obligate intracellular pathogens is extremely difficult, as these organisms possess ... -
The Diabetes Care Cascade in Sri Lanka: An Analysis of Losses, Disparities, and Opportunities for Improved Health System Outcomes
(2025-06)Sri Lanka has one of the highest prevalence rates of diabetes, and improving diabetes control is a national priority. The care cascade framework, a tool for evaluating diabetes control and identifying system gaps, has ... -
Comprehensive review on growth hormone (GH) mutations and sequence variants in children with growth hormone deficiency
(2025-04-19)Growth hormone (GH) is a vital peptide hormone respon sible for regulating growth, development and numerous metabolic functions in humans and other vertebrates. Comprising 190 amino acids, GH is synthesized and secreted ... -
Women's Participation in Sri Lanka's Blue Economy: An Exploration of the Influence of Socio-Economic Factors
(2025-01)The purpose of this paper was to examine the effect of socio-economic factors on women’s engagement in the blue economy of Sri Lanka, an important sector with low female representation and limited empirical studies. ... -
Reflections on transfemoral TAVI in dextrocardia with severe aortic regurgitation: Navigating anatomical complexity, off-label innovation, and future directions
(2025-06)This reflective article explores the first reported case in literature of a transfemoral transcatheter aortic valve implantation (TAVI) in a dextrocardiac patient with severe aortic regurgitation (AR), left-sided superior ... -
Exploring the Rich Diversity of 24 Unique Yam Varieties in Sri Lanka
(2025-02-10)This study explores the diverse varieties of yams cultivated and consumed in Sri Lanka, focusing on their distinct characteristics, nutritional value, and culinary applications. Yams such as Kaha Gahala, Kukulu Ala, Katu ... -
Retention and fracture of a hydrophilic radial artery sheath due to severe spasm
(2012)Worldwide, there is increasing interest in transradial intervention, as it appears safer, more cost-effective and is the preferred access route for patients over transfemoral intervention. The favorable neuroanatomical ... -
Cross-sectional study of lipoprotein(a) and the severity of coronary artery disease, cerebrovascular disease, and peripheral vascular disease in a group of South Asian patients
(2025-02-27)Background Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease (CAD), cerebrovascular disease (CVD), and peripheral vascular disease (PVD), remain the leading cause of death globally. South ... -
Data-driven insights for improving library services: a big data approach to books circulation at kotelawala defense university
(2024-10-17)This research explores the application of Big Data-driven analytics to understand, optimize, and enhance book circulation trends at the Library of Kotelawala Defense University. By leveraging advanced technologies, machine ... -
Assessment of In vitro Anti Inflammatory Activity: A Comprehensive Review of Methods, Advantages, and Limitations
(2025-02-26)Inflammation is a vital biological response that plays an important role during tissue repair and defense against infections. A range of transcription factors (including NF-KB and AP-1), enzymes (Cycooxygenase-2 (COX-2) ... -
The role of the teachers, working in special needs children’s classrooms that ensure quality learning outcomes for all learners
(2024-03)The teachers, serving in the special classrooms have to play a major role in further extending their services focusing on the special needs of children’s achievement in education. “The term disability is encompassed by ... -
Investigating Information Gaps that Impact on the Economic Efficiency of Offshore Fisheries Sector in Sri Lanka
(2015-11-13)Offshore fishery in Sri Lanka is one of the most potential resources that can be developed to meet the future demands for the economic efficiency. To accomplish this, technology and information have a major role to play ... -
Systematic Review On Dynamic Scheduling in Timetable Automation
(2025-01)Dynamic scheduling in timetable automation poses a significant challenge for educational institutions, which requires adaptability and efficiency. This paper proposes a multi-agent system (MAS) using the Java Agent Development ... -
Leveraging Underutilized Sri Lankan Fruits in the Fight against Autoimmune Disorders
(2025-01-17)The potential of underutilized plant species to improve food security, health, eco-nomic output, and the environment has not been fully realized. Sri Lanka an island on the Indian Ocean is home to numerous plant species ...
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