In Vitro Evaluation Of Sun Screen Activity And Phytochemical Screening Of Methanolic Leaf Extract Of Magnolia Figo

Abstract

Abstract: Magnolia figo (Local name: “Madanakama”) is a native Chinese plant, which belongs to Family Magnoliaceae. Although, different parts of the plant have been used as a treatment for several types of disease conditions such as malaria, cardiovascular diseases and as a strengthening agent for sexual virility in traditional medicine. The aims of the present study were to evaluate the sunscreen activity and to qualitatively analyze the phytochemicals present in methanolic leaf extract of Magnolia figo. Collected leaves were air-dried, powdered and macerated in methanol. The filtrate was evaporated to dryness and subjected to freezedrying process. The SPF values of methanolic extract of Magnolia figo and the reference agent; Dermatone® were analyzed in vitro by using spectrophotometric method. The results exhibited that 2.00 mg/mL methanolic extract of Magnolia figo has high sun protection activity (29.94). The dose response relationship of Magnolia figo and Dermatone® was analyzed according to concentration series of each, respectively. In the current study EC 50 was calculated to methanolic leaf extract of Magnolia figo (0.9135) which is lower than Dermatone® (1.7820) suggesting that the potency of methanolic leaf extract of Magnolia figo is higher than the reference agent. According to the phytochemical screening, methanolic leaf extract of Magnolia figo was rich in alkaloids, phenols, tannins, terpenoids, flavonoids, steroidal glycosides and saponins. The results concluded that leaf extract of Magnolia figo possesses marked sunscreen activity which exhibits its potential use for development of sunscreen formulations.