| dc.description.abstract | Abstract: Magnolia figo (Local name: “Madanakama”) is a native Chinese plant, which belongs
to Family Magnoliaceae. Although, different
parts of the plant have been used as a treatment
for several types of disease conditions such as
malaria, cardiovascular diseases and as a
strengthening agent for sexual virility in
traditional medicine. The aims of the present
study were to evaluate the sunscreen activity
and to qualitatively analyze the phytochemicals
present in methanolic leaf extract of Magnolia
figo. Collected leaves were air-dried, powdered
and macerated in methanol. The filtrate was
evaporated to dryness and subjected to freezedrying process. The SPF values of methanolic
extract of Magnolia figo and the reference agent;
Dermatone® were analyzed in vitro by using
spectrophotometric method. The results
exhibited that 2.00 mg/mL methanolic extract of
Magnolia figo has high sun protection activity
(29.94). The dose response relationship of
Magnolia figo and Dermatone® was analyzed
according to concentration series of each,
respectively. In the current study EC 50 was
calculated to methanolic leaf extract of Magnolia
figo (0.9135) which is lower than Dermatone®
(1.7820) suggesting that the potency of
methanolic leaf extract of Magnolia figo is higher
than the reference agent. According to the
phytochemical screening, methanolic leaf
extract of Magnolia figo was rich in alkaloids,
phenols, tannins, terpenoids, flavonoids,
steroidal glycosides and saponins. The results
concluded that leaf extract of Magnolia figo
possesses marked sunscreen activity which
exhibits its potential use for development of
sunscreen formulations. | en_US |
