A study on the anti-inflammatory effect of a novel preparation, Sudarshana Syrup (SS) in Wistar rats

Abstract

This study investigated the anti-inflammatory potential of the Sudarshana syrup (SS) in Wistar rats after oral administration (6.5ml / kg). This was done using the carrageenan-induced paw edema method (acute inflammatory model) Data was analyzed statistically by analysis of variance (ANOVA). Results with p < 0.05 were considered as significant. The maximum inhibition, 88.5 % was noted after 5th hour of test drug, whereas the Indomethacin produced 96.2 % inhibition. A statistical significant reduction (p<0.05) of paw oedema was noted at every hour when compared with the negative control group.