Assessment of Setup-errors in 3d-conformal Radiotherapy for Head and Neck Cancer Patients Using an Electronic Portal Imaging Device

Abstract

Patient setup is crucial in radiotherapy since treatment is delivered as fractionated treatment over a period of time. Using own institutional margins by considering the setup errors will provide better radiotherapy outcome. Therefore, this study aims to assess set up errors for head and neck cancer patients using an electronic portal imaging device at Apeksha Hospital, Maharagama, Sri Lanka. A total of 101 head and neck cancer patients who were immobilized with thermoplastic mask were selected in this study. Stored data from July 2021 to July 2022 were obtained from ARIA patient management system in the Varian 2300CD Unit at Apeksha Hospital. In order to calculate systematic and random errors, translational errors in all directions were collected utilizing 303 pairs of orthogonal portal images. Moreover, three different algorithms were used to obtain the margin of clinical target volume (CTV) to planning target volume (PTV). The estimated systematic and random errors in the directions of antero-posterior, superior-inferior and medio-lateral are 0.13 cm, 0.10 cm and 0.08 cm, and 0.22 cm, 0.21 cm, and 0.19 cm respectively. Less than 0.5 cm margin were obtained by applying three different algorithms. This study indicates that using a 0.5 cm margin for head and neck cancer patients treating in 2300CD Varian Unit at Apeksha Hospital is safe. Further, this study recommends to developing institutional CTV to PTV margin for all sites of cancer to reduce unnecessary radiation to the surrounding normal healthy tissues.