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Can Clomiphene Citrate Improve the Quality of Seminal Fluid Parameters in Idipathic Oligoasthenoteratozoospermic Males

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dc.contributor.author Fernando, HHLK
dc.contributor.author Senevirathne, R
dc.contributor.author Rodrigo, PM
dc.contributor.author Weerasooriya, TR
dc.date.accessioned 2018-06-01T09:38:03Z
dc.date.available 2018-06-01T09:38:03Z
dc.date.issued 2014
dc.identifier.uri http://ir.kdu.ac.lk/handle/345/1537
dc.description article full text en_US
dc.description.abstract Introduction: Male infertility is a rising problem worldwide. Idiopathic male infertility is responsible for 31% of all male infertility. Among them 44% is due to Idiopathic Oligo Astheno Terotozoospermia (iOAT) syndrome. The role of medical treatment in managing iOAT syndrome is controversial . But there are accumulating evidence of the efficacy of Clomiphene citrate on treating iOAT syndrome. Objective: To determine the efficacy of Clomiphene Citrate therapy in improving seminal fluid parameters of a group of male patients with iOAT syndrome. Study type: a comparison study was done using retrspective data. Method: This study was conducted in the Reproductive biology laboratory of the Faculty of Medicine, Galle. Medical records of 52 patients presented with iAOT syndrome, treated with clomiphene citrate were screened using the exclusion and inclusion criteria. The pre-tratment and post-treatment seminal fluid analysis of the patients were compared using the paired t- teast. All the patients were given clomiphene citrate 50mg per day in divided doses for minimum of 3 months. Post-treatment seminal fluid analysis were done at the end of the 4th month of commencing the treatments. Results: Sperm concentration, sperm total count, normal morphology, motility and viability are improved significantly (p<0.001). The improvement of the volume is not significant (p> 0.001) Conclusion: Clomiphene citrate improves the sperm concentration, total count, normal morphology, motility and viability in a group of selected male patients with iOAT syndrome but the volume. en_US
dc.language.iso en en_US
dc.subject clomiphene citrate en_US
dc.subject ioat en_US
dc.subject male infertility en_US
dc.title Can Clomiphene Citrate Improve the Quality of Seminal Fluid Parameters in Idipathic Oligoasthenoteratozoospermic Males en_US
dc.type Article Full Text en_US
dcterms.bibliographicCitation Fernando, H. et al. (2014) ‘Can Clomiphene Citrate Improve the Quality of Seminal Fluid Parameters in Idipathic Oligoasthenoteratozoospermic Males’, in KDU International Research Symposium Proceedings. General Sir John Kotelawala Defence University, pp. 42–45. Available at: http://ir.kdu.ac.lk/handle/345/1537.
dc.identifier.journal KDU IRC en_US
dc.identifier.issue FOM en_US
dc.identifier.pgnos 42-45 en_US


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