| dc.description.abstract | The peels of Musa paradisiaca apply to a wide range of applications, including antimicrobial
applications, the production of face masks, hair masks, and biofuel. This study
aimed to determine the antimicrobial activity of aqueous, ethanolic, and methanolic
extracts of M. paradisiaca peels against selected oral pathogens. Ethanolic and methanolic
extracts were concentrated by evaporating evaporation at room temperature. Powder
(500 mg) was dissolved in 1 ml of 1% Dimethyl Sulfoxide (DMSO) for agar well di usion
assay. Gentamycin, Vancomycin and Fluconazole were used as positive controls for Gramnegative
bacteria, Gram-positive bacteria and Candida respectively. DMSO (1%) served as
the negative control. Inhibitory zones were measured after overnight incubation at 37 C.
The Minimum Inhibitory Concentration (MIC) of the extracts was determined using a
broth dilution assay. S.aureus, E. coli, K. pneumonia, and C. albicans exhibited mean
inhibitory zone diameters of 23 1.0 mm, 17 3.0 mm, 21 2.0 mm, and 5.6 0.0
mm, respectively for methanol extract at 500 mg/ml. The respective controls exhibited
mean zone of inhibition diameters of 26 0.3mm, 20 0.1 mm, 28 0.0mm, and 12
0.6 mm, respectively. For the ethanolic extract, K. pneumonia , S. aureus, E. coli, and
C. albicans exhibited 27 0 mm, 18 1.0 mm, 16 3.0 mm, and 8 0.0mm diameter
mean inhibitory zones respectively, at 500 mg/ml. The respective controls exhibited mean
zone of inhibition diameters of 28 0.2 mm, 26 0.0 mm, 20 0.4 mm, and 12 0.6
mm. The aqueous extract did not exhibit inhibitory e ects against tested microorganisms.
For the ethanol extract, MIC against S. aureus and E. coli was found to be 125 mg/ml.
For methanolic extract, MIC against K. pneumoniae was 125 mg/ml. The methanolic and
ethanolic extracts from M. paradisiaca peel have potential antimicrobial properties against
the tested microbes, comparable to that of the positive controls. | en_US |
