dc.description.abstract | Type 2 Diabetes Mellitus (T2DM) and Knee Osteoarthritis (KOA) are chronic
diseases that frequently co-exist. This cross-sectional study was conducted to find
out the association between T2DM and KOA among patients attending the
Rheumatology and Rehabilitation Clinic, University Hospital, Kotelawala Defence
University. KOA patients (n=106) were evaluated using an interviewer
administered questionnaire. Fasting Blood Sugar (FBS), Glycosylated Haemoglobin
(HbA1c) and Erythrocyte Sedimentation Rate (ESR) were measured. Symptoms for
T2DM were identified. Patients were categorized in to three groups with regards to
diabetes status: normal, prediabetes and diabetes. Body Mass Index values were
also categorized in to three categories as Underweight and Normal (Group 1),
Overweight (Group 2), Obese 1 and Obese 2 (Group 3). Mean age of KOA patients
was 61.6±9.2 years (40 to 86 years). Majority were females (77.3%). Among the KOA
patients 27.4% were non-diabetes, 40.6% were prediabetes and 32.1% were
diabetes. High frequency reported among Group 3 BMI (68.8%) category. Among
KOA patients 48.1% with hypertension, 49.6% with family history of T2DM were
reported. The mean of HbA1c (%), FBS (mg/dL) and ESR (mm/hr.) for the
population were 5.91 ±0.68, 25.06±27.94, 26.98 ±14.17 respectively. Having a
family history of T2DM, overweight and obese categories showed a significant
association (p<0.05) between T2DM and KOA. In conclusion, increased age, female
gender, BMI (Overweight and obese) and a family history of T2DM are the
contributory factors for developing T2DM among KOA patients in study. Further,
Overweight, and obese BMI and having a family history of T2DM can use to monitor
the KOA patients for developing of T2DM for the population in this present study. | en_US |