| dc.description.abstract | Magnetic Resonance Imaging (MRI) can be treated as one of the best modalities
for volume determination of soft tissue structures. As age and sex show a
conspicuous influence upon the ocular volume, this study was aimed to evaluate
the age and gender dependent variations in ocular volumes of Sri Lankan adults
using MRI. This study was conducted with 200 adult brain MR images, reported
as normal within the age of 18–90 years at the National Hospital, Sri Lanka.
Ocular volumes were measured separately as 2D and 3D measurements by using
an equation and software, respectively. Statistically significant differences in
both ocular volumes were found with gender (p<0.05) in both 2D and 3D volume
analysis methods. On the contrary, while 3D measurements show a significant
linear relationship with age in both eyeball volumes, 2D measurement showed
a significant linear relationship with age only in the left ocular volume (p<0.05).
Weak negative correlations were found with age in right ocular volume in both
2D(r=-0.121) and 3D(r =-0.168) measurements and in left ocular volume in both
2D(r=-0.151) and 3D(r =-0.179) measurements. Furthermore, a statistically
significant difference was found between the two volume measurement
methods (p<0.05) suggesting a partiality between them. Therefore,
standardization between the two methods is required. This study concludes that
both age and gender have a significant impact on ocular volumes. Since there are
no recommended reference values for ocular volumes of the Sri Lankan adult
population, this study may serve as normal reference values for the adult
population in Sri Lanka. It also supports ophthalmologists and radiologists to
quantitatively evaluate ocular pathologies. | en_US |
