| dc.description.abstract | Lesions involving nasal cavity (NC), paranasal
sinuses (PNS) and nasopharynx consist of a wide
variety of inflammatory, non-neoplastic and
neoplastic lesions. Even though they are common
in Sri Lanka, proper data are scarce. The study
aims to determine various histopathological
patterns of NC, PNS and nasopharyngeal
lesions and their demography with regard to
age and sex. A retrospective analytical study
was carried out in all patients who underwent
biopsies of the above lesions presented to
ENT unit at NHSL from 1.1.2015 to 31.12.2017.
From 238 patients, the commonest site was the
NC (51.06%) followed by PNS (43.9%). Male
to female ratio was 1.38:1. 79.6% were nonneoplastic,
from which 88.9% were inflammatory
and 7.3% were fungal, where mucomycosis and
rhinosporidiosis being the commonest. Out of the
neoplastic conditions (20.4%), 54.1% were benign,
with inverted papilloma being the commonest
(42.3%), commonly seen in 6th and 7th decades
with a male predominance, followed by
angiofibroma(15.3%). Squamous cell carcinoma is
the commonest malignancy (40.9%), common in
7th and 8th decades with a male predominance,
followed by adenocarcinoma (18.18%), adenoid
cystic carcinoma (9%) and non- Hodgkin’s B
cell lymphoma (9%). Internationally, benign and
malignant neoplasms are more common in 4-5th
decades and 5-6th decades respectively. But in our
study both benign and malignant neoplasms were
found approximately two decades later in life.
This may be either due to late presentation. Hence
we recommend a thorough ENT examination at
the earliest presentation. Further multicentre
studies are needed. | en_US |
