Browsing by Author "Goonasekara, CL"
Now showing items 1-10 of 10
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Conservation of in-silico Predicted Epitopes of SARS-CoV-2 and Other Native Corona Viruses from Different Geographic Regions
Karunathilake, ATAD; Lasanthi, NPDS; Goonasekara, CL; Seneviratne, SS (2021) -
The Effect of Pre-existing Immunity Against Japanese Encephalitis Virus on the Severity of Dengue Disease
Pushpakumara, BPD (2021) -
Immunogenicity of Dengue E-protein Peptides Modified with Para-nitro Phenylalanine
Nadugala, M; Premaratne, PH; Goonasekara, CL (2023-09)Few conserved epitopes from the Envelope (E) protein of the dengue virus have previously been identified to show a broader immunogenicity and neutralization towards all the fours dengue virus serotypes. Inclusion of an ... -
In vitro Antioxidant and Anti-inflammatory Activity of “Denabadiya Kasaya”: A Traditional Polyherbal Formulation Used for the Treatment of Fever Including Dengue
Handagala, JK; Kumarasinghe, N; Goonasekara, CL; Kuruppu, AI (2023-09)“Denabadiya Kasaaya” is an intricate formulation rooted in Sri Lankan traditional medicine, crafted from a blend of eight distinct herbs which is prescribed for fever and flu like symptoms including dengue fever. We ... -
Molecular Characterization and Phylogenetic Relationship of SARS-CoV-2 Strains Infecting a NAVY Cohort during the First Wave of the COVID-19 in Sri Lanka
Jayasinghearachchi, HS; Govindapala, DS; Nakkawita, WMID; Premaratne, PH; Goonasekara, CL; Kawyangana, DGP; Chathuranga, KWT; Kulasekara, US; De Silva, AD (2021) -
Phylogenetic and Conservational Analyses of Dengue Non-Structural Protein 1
Pushpakumara, PD; Premarathne, PH; Goonasekara, CL (2015)The variability in the host immune responses against infections by different strains of Dengue virus (DENV), due to their sequence heterogeinity, is a huge obstacle in disease management and development of an effective ... -
Potential of a Herbal Preparation Used in Indigenous Medicine to Neutralize Nba nojo Venom: Example from Wet Zone, Sri Lanka
Silva, MM; Senevirathne, SS; Weerakoon, DK; Goonasekara, CL (2015)The venom neutralizing ability of a herbal preparation used in traditional medicine was characterized. The preparation is known for successful treatment of Naj a naj a and Daboia russelii envenomation, particularly in the ... -
Potentialities of Bioinformaticaly Predicted Linear B-cell Epitopes on Dengue prM Protein
Nadugala, MN; Premaratne, PH; Goonasekara, CL (2015)Predicting linear B-cell epitopes using bioinformatic tools is attractive as an initial step for screening such epitopes with potential use in Dengue (DENV) diagnosis and therapeutics, for their high speed and low cost. ... -
A Preliminary Study Conducted on a Traditional Formulation used for the Treatment of Dengue
Handagala, JK; Kumarasinghe, NP; Goonasekara, CL; Kuruppu, AI (2022)Currently, around the globe, there are no effective drugs for the treatment of acute dengue infection. Even though a vaccine was licensed recently, it was found to have limited efficacy. Scientists are currently seeking ... -
Validation of Loop Mediated Isothermal Amplification Technique (LAMP) to Diagnose Tuberculosis (TB) in Sri Lanka.
Goonasekara, CL; Usgodaarachci, B; Alvitigala, J; Navarathna, V (2012)