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Now showing items 2931-2950 of 5569
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In silico Study of the Binding Affinities of Acetylcholinesterase and Synthetically Viable Coumarin Analogs
(2018)Acetylcholinesterase (AChE) is a serine hydrolase that is responsible for the hydrolysis of acetylcholine-a neurotransmitter associated with the transmission of nerve impulses. The reversible inhibition of AChE can be ... -
In Silico Study of the Computationally Designed Novel Vinca Alkaloid Derivatives VADRPA01 and VADRPH01 Effects on Calmodulin and Calmodulin Dependent Ca2+ Transport ATPase
(2023-09)Vinblastine was the first Vinca Alkaloid (VA) with antiproliferative properties discovered in plant C. roseus. The ability of VA drugs to bind with the Calmodulin (CaM) and Calmodulin-dependent Ca 2+ transport ATPase ... -
In This Nation of Spitters
(2014) -
In vitro Analysis of the Anti-in ammatory Activity of Sri Lankan Bees’ Honey, Aloe vera, their Combination, and the Development of a Topical Anti-in ammatory Gel
(2023-09)Clinicians and scientists are on the lookout for the development of safer, sustainable alternatives for topical corticosteroids in treating in ammatory skin diseases due to the potential complications associated with ... -
In vitro Anti-inflammatory Activity of Endemic Artocarpus nobilis Thw Found in Sri Lanka
(2021-12-29)Aims: To investigate in vitro anti-inflammatory activity of aqueous, methanol, dichloromethane, and hexane extracts of Artocarpus nobilis Thw. leaves and stem bark using heat-induced protein denaturation test (egg ... -
In vitro Anti-Inflammatory Activity of Leaves of Jeffreycia zeylanica Using the Egg Albumin Denaturation Method and Human Red Blood Cell Stabilization Method
(2023-11-25)Aims To investigate the in vitro anti-inflammatory activity of aqueous, methanol, dichloromethane (DCM), and hexane extracts of Jeffreycia zeylanica leaves extracts. In vitro protein (egg albumin) denaturation method and ... -
In Vitro Antibacterial Activity of Hexane, Chloroform and Methanolic Extracts of Different Parts of Acronychia Pedunculata Grown in Sri Lanka.
(2016-08-31)This study accessed the antibacterial potential in vitro of hexane, chloroform and methanol extracts made from leaves, stem bark, flowers, seeds or roots of Sri Lankan grown Acronychia pedunculata plant against two Gram ... -
In vitro Antioxidant Activity and α- Amylase Inhibitory Activity of Methanolic Extract of Sri Lankan Marine Brown Algae Chnoospora minima (Hering 1841)
(2018)Chnoospora minima (Herring) is a brown algae that belongs to Family Scytosiphonaceae. The current study investigated the total phenolic (TP), total flavonoid contents (TFC), antioxidants and anti-amylase activity of ... -
In Vitro Antioxidant Activity of Methanolic Extracts of Leaves of Indigofera Indica and Stems of Stereospermum Suaveolens Grown in Sri Lanka
(2015-08-03)Oxidative stress due to free radicals plays a fundamental role in pathogenesis of several human diseases. Accordingly, wide search is operative to discover novel and potent antioxidants to be used as prophylactics and ... -
In vitro Antioxidant and Anti-inflammatory Activity of Leaf and Stem Bark of Selected Mangifera Species in Sri Lanka
(2022)Mangifera indica (MI), locally known as ‘Amba’ in Sinhalese is the richest species of Mangifera found in Sri Lanka with its multiple varieties. This research determined the antioxidant and anti-inflammatory effects by ... -
In vitro Antioxidant and Anti-inflammatory Activity of “Denabadiya Kasaya”: A Traditional Polyherbal Formulation Used for the Treatment of Fever Including Dengue
(2023-09)“Denabadiya Kasaaya” is an intricate formulation rooted in Sri Lankan traditional medicine, crafted from a blend of eight distinct herbs which is prescribed for fever and flu like symptoms including dengue fever. We ... -
In vitro Antioxidant, Anti-amylase, Anti-glycation Potentials and Mineral Elements of an Endangered Plant Syzygium caryophyllatum L. Alston (Sinhala: Heendan)
(2018)Syzygium caryophyllatum L. (Family: Myrtacea) Heendan in Sinhala is a red listed plant which is yet to be exploited as a source of functional food. Therefore, in the present study, antioxidant, antiglycation and ... -
In Vitro Antirheumatoid Arthritic Activity of Aqueous Root Extract of Clitoria Ternatea
(2014-11-22)In ethano medicine, roots of Clitoria ternatea (Family: Fabaceae) is claimed to possess antirheumatoid arthritic activity. However, this claim has not been scientifically tested and validated yet. This study assessed the ... -
In vitro Bioactivity of Methanol Extracts of Elaeocarpus serratus Leaves and Fruit
(2022)Plants are getting significant attention globally and the worldwide annual market for herbal products is ~USD 60 billion. Elaeocarpus serratus which is an underutilized fruit crop in Sri Lanka was selected for scientific ... -
In vitro Cytotoxicity Assessment of Glyphosate on the Vero Cell Line
(2023-09)Glyphosate, a widely used broad-spectrum herbicide in agricultural practices, has been a subject of ongoing debate regarding its potential adverse effects on human health. This research aimed to investigate the cytotoxicity ... -
In Vitro Effects of Aqueous Extracts of Five Sri Lankan Medicinal Plants on Human Erythrocyte Membrane Stabilization Activity
(2015-06-01)In vitro assessment of human erythrocyte membrane stabilisation activity of water extracts of Clitoria ternatea (Family: Fabaceae) roots, stem bark extracts of Stereospermum Suaveolens (Family: Bignoniaceae) and Oroxylum ... -
In vitro Evaluation of Anti-Inflammatory and Antibacterial Properties of Tuberous Roots of Mirabilis Jalapa Linn. Found in Sri Lanka
(2023-09)The Four-O’clock plant, also known as Mirabilis jalapa Linn. is a well-known ornamental plant prized for its folklore remedies in many countries around the world. The objective of the current study was to evaluate the ...