Browsing Medicine by Issue Date
Now showing items 1-20 of 30
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Stem Cell Manipulation with Plasmid-Based Transcription Factor Over-Expression Systems to Successfully Generate Pre-Specified Cells Fates in-vitro; Proof of Concept of in-vitro Stem Cell Fate Reprogramming Using cDNA Vectors
(2022-09-29)The differentiation of stem cells in a controlled fashion is essential to achieve a predefined daughter cell types required for research or regenerative therapies. Transcription factors play a key role in switching ... -
Cytotoxic Effects of Syzygium aromaticum Leaf Extract against Aedes albopictus Cells
(2022-09-29)Syzygium aromaticum consists of anti-microbial and anti-parasitic activity. S. aromaticum is rich in many phytochemicals such as eugenol, terpenes, and phenolic compounds. In this research, we tested the cytotoxicity of ... -
Association of Sociocultural and Demographic Factors on Attitudes of Teaching Sexual and Reproductive Health in Science and Health Science Teachers in Dehiowita Educational Zone in Kegalle District, Sri Lanka
(2022-09-29)School based reproductive health education depends on teachers, students and other factors related to schools. Factors related to teachers can be assessed through knowledge, attitudes and practice of them. A descriptive ... -
A Relapsed Case of Disseminated Histoplasmosis – A Case Report from Sri Lanka
(2022-09-29)Histoplasma capsulatum is a soil saprophyte which is now considered to be endemic in Southeast Asia and Southern Europe. It is a thermally dimorphic fungus seen in damp soil contaminated with bat guano and bird excreta. ... -
Activation of Latent Melioidosis Infection in an Immunocompromised Patient: A Case Report
(2022-09-29)Melioidosis causes suppurative infection with local abscesses and the reservoirs of the organism; Burkholderia pseudomallei are soil, fresh water and paddy fields. The diagnosis is made by isolating the organism through ... -
Knowledge and Selected Practices of Paid Bystanders Regarding Patient Care and Personal Protection in Colombo-North Teaching Hospital, Ragama, Sri Lanka
(2022-09-29)The dearth of studies on paid bystanders who figure prominently in caregiving for inward patients in Sri Lankan hospitals led us to assess their knowledge and selected practices regarding patient care and personal ... -
Complete Genome Sequencing and Phylogenetic Analysis of Dengue Type 1 Isolated from Sri Lanka from 1983-2014
(2022-09-29)Sri Lanka faces regular outbreaks of dengue and from 1989 onwards dengue became endemic to the country. All four serotypes of dengue have been recorded, and the outbreak of dengue virus 1 (DENV 1) in 2009 resulted in the ... -
Assessment of Knowledge and Clinical Skills for Minimum Image Set in POCUS for Efast and Lung Scan among Sri Lankan Emergency Medicine Trainees
(2022-09-29)Point of care ultrasound (POCUS) is used by clinicians to answer specific questions to expedite emergency care until a comprehensive assessment can be done. Minimal image set in POCUS is considered the most critical ... -
The Utility of Rotational Thromboelastometry (ROTEM) in Identifying Envenomation Following Cobra Bites
(2022-09-29)The cobra is one of the highly venomous snakes in Sri Lanka. Cobra bites are not known to cause haemato-toxicity, except in some studies that have shown a transient coagulopathy by nonclotting 20-minute Whole Blood ... -
Overweight and Obesity: Knowledge, Attitudes and Recognition by Patients and Medical Practitioners
(2022-09-29)The World Health Organization describes obesity as the most visible but neglected public health problem. We assessed the knowledge, perception and attitudes towards obesity among overweight/obese patients and the recognition ... -
Integrating Mindfulness Based Techniques into Cognitive Behaviour Therapy (CBT) for Obsessive-Compulsive Disorder (OCD): A Case Description
(2022-09-29)Sam was a patient admitted to the psychiatry department of a tertiary care hospital due to the worsening of his OCD symptoms. He had been to many psychiatrists and psychotherapists for close to six years. His OCD symptoms ... -
Evaluating Bioequivalence of Two Formulations of Metformin Hydrochloride US 500 mg XR Oral Tablets under Fasting Conditions in Healthy Sri Lankan Subjects
(2022-09-29)The WHO mandates therapeutic interchangeability of multi-source oral medicines with the respective innovator be proven either by bioequivalence (BE) or biowaiver. This study aimed to evaluate the bioequivalence of two ... -
Prediction of Newborn Anthropometric Parameters using Maternal Anthropometry at Tertiary Care Maternity Hospital in Galle District, Sri Lanka
(2022-09-29)The state of maternal nutrition, denoted by maternal anthropometric parameters, is found to play a pivotal role in determining new-born anthropometric parameters. This study was conducted to predict new-born anthropometric ... -
Melioidosis: A Deadly Disease Mimicking Leptospirosis Reported from a Highly Endemic Area of Sri Lanka
(2022-09-29)Melioidosis is endemic in Sri Lanka. We present a case of melioidosis which led to diagnostic confusion and an unfavourable outcome. A 53-year-old paddy farmer from Kurunegala was admitted to the University Hospital, KDU ... -
Antibiotic Sensitivity of Uropathogens to First Line Antibiotics: A Laboratory-Based Analysis from a University Hospital in Sri Lanka
(2022-09-29)Outpatient treatment of urinary tract infections is compromised due to rapid development of resistance to first line antimicrobials leading to increased healthcare cost. Continuous resistance surveillance is important ... -
Filarial Infections among Migrant Workers Employed in Steel Factories in Gampaha District, Sri Lanka
(2022-09-29)In 2016, WHO declared Sri Lanka as a country that eliminated lymphatic filariasis (LF) as a public health problem. Influx of migrant workers from neighbouring countries which are still endemic for LF has been reported ... -
Review on Antidiabetic Potency of Family Aristolochiaceae Using the Diabetic Rat Model, α-Glucosidase, and α-Amylase Inhibitory Assays
(2022-09-29)The plant species in the family Aristolochiaceae consists of various important bioactive compounds, and they are used as functional ingredients in the development of therapeutic agents to act against diseases including ... -
Sexual Dimorphism in Sri Lankan Saw Scaled Viper Based on the Mensural and Pholidosis Characters
(2022-09-29)Sri Lankan SSV was recorded as a sub species of Echis carinatus named as Echis carinatus Sinhaleyus by Deraniyagala in 1951. The study aimed to explore the sexual dimorphism in Sri Lankan saw scaled viper based on the ... -
Comparative Evaluation of Antibiotic Resistant Alert Organisms Detected from COVID-19 and non-COVID-19 Patients during Pandemic and Pre-Pandemic Era
(2022-09-29)Antibiotic resistant alert organism surveillance is essential for early prediction of outbreaks, timely investigation, and for implementation of control measures. The aim was to compare the rates of seven specified ... -
Ayurveda Intervention of the Management on Dvajabhanga wsr Erectile Dysfunction: A Systematic Review
(2022-09-29)Ayurveda classical texts have mentioned that Dvajabhanga can be correlated with Erectile Dysfunction (ED) in modern medicine. In this study the PICO model was used to formulate the research question. This systematic ...